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Reversal of diabetes following transplantation of an insulin-secreting human liver cell line: Melligen cells
As an alternative to the transplantation of islets, a human liver cell line has been genetically engineered to reverse type 1 diabetes (TID). The initial liver cell line (Huh7ins) commenced secretion of insulin in response to a glucose concentration of 2.5 mmol/l. After transfection of the Huh7ins c...
Autores principales: | Lawandi, Janet, Tao, Chang, Ren, Binhai, Williams, Paul, Ling, Dora, Swan, M Anne, Nassif, Najah T, Torpy, Fraser R, O’Brien, Bronwyn A, Simpson, Ann M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445011/ https://www.ncbi.nlm.nih.gov/pubmed/26029722 http://dx.doi.org/10.1038/mtm.2015.11 |
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