The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis

We sequenced and analyzed Shigella dysenteriae strain Sd1617 serotype 1 that is widely used as model strain for vaccine design, trials and research. A combination of next-generation sequencing platforms and assembly yielded two contigs representing a chromosome size of 4.34 Mb and the large virulenc...

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Autores principales: Vongsawan, Ajchara A., Kapatral, Vinayak, Vaisvil, Benjamin, Burd, Henry, Serichantalergs, Oralak, Venkatesan, Malabi M., Mason, Carl J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Research Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445032/
https://www.ncbi.nlm.nih.gov/pubmed/25743074
http://dx.doi.org/10.1093/femsle/fnv011
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author Vongsawan, Ajchara A.
Kapatral, Vinayak
Vaisvil, Benjamin
Burd, Henry
Serichantalergs, Oralak
Venkatesan, Malabi M.
Mason, Carl J.
author_facet Vongsawan, Ajchara A.
Kapatral, Vinayak
Vaisvil, Benjamin
Burd, Henry
Serichantalergs, Oralak
Venkatesan, Malabi M.
Mason, Carl J.
author_sort Vongsawan, Ajchara A.
collection PubMed
description We sequenced and analyzed Shigella dysenteriae strain Sd1617 serotype 1 that is widely used as model strain for vaccine design, trials and research. A combination of next-generation sequencing platforms and assembly yielded two contigs representing a chromosome size of 4.34 Mb and the large virulence plasmid of 177 kb. This genome sequence is compared with other Shigella genomes in order to understand gene complexity and pathogenic factors.
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spelling pubmed-44450322015-06-18 The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis Vongsawan, Ajchara A. Kapatral, Vinayak Vaisvil, Benjamin Burd, Henry Serichantalergs, Oralak Venkatesan, Malabi M. Mason, Carl J. FEMS Microbiol Lett Research Letter We sequenced and analyzed Shigella dysenteriae strain Sd1617 serotype 1 that is widely used as model strain for vaccine design, trials and research. A combination of next-generation sequencing platforms and assembly yielded two contigs representing a chromosome size of 4.34 Mb and the large virulence plasmid of 177 kb. This genome sequence is compared with other Shigella genomes in order to understand gene complexity and pathogenic factors. Oxford University Press 2015-01-28 2015-03 /pmc/articles/PMC4445032/ /pubmed/25743074 http://dx.doi.org/10.1093/femsle/fnv011 Text en © FEMS 2015. http://creativecommons.org/licenses/by-nc/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Research Letter
Vongsawan, Ajchara A.
Kapatral, Vinayak
Vaisvil, Benjamin
Burd, Henry
Serichantalergs, Oralak
Venkatesan, Malabi M.
Mason, Carl J.
The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis
title The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis
title_full The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis
title_fullStr The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis
title_full_unstemmed The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis
title_short The genome of Shigella dysenteriae strain Sd1617 comparison to representative strains in evaluating pathogenesis
title_sort genome of shigella dysenteriae strain sd1617 comparison to representative strains in evaluating pathogenesis
topic Research Letter
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445032/
https://www.ncbi.nlm.nih.gov/pubmed/25743074
http://dx.doi.org/10.1093/femsle/fnv011
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