SOXE transcription factors form selective dimers on non-compact DNA motifs through multifaceted interactions between dimerization and high-mobility group domains

The SOXE transcription factors SOX8, SOX9 and SOX10 are master regulators of mammalian development directing sex determination, gliogenesis, pancreas specification and neural crest development. We identified a set of palindromic SOX binding sites specifically enriched in regulatory regions of melano...

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Detalles Bibliográficos
Autores principales: Huang, Yong-Heng, Jankowski, Aleksander, Cheah, Kathryn S. E., Prabhakar, Shyam, Jauch, Ralf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445065/
https://www.ncbi.nlm.nih.gov/pubmed/26013289
http://dx.doi.org/10.1038/srep10398

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