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Evaluation of New Dihydrophthalazine-Appended 2,4-Diaminopyrimidines against Bacillus anthracis: Improved Syntheses Using a New Pincer Complex

The synthesis and evaluation of ten new dihydrophthalazine-appended 2,4-diaminopyrimidines as potential drugs to treat Bacillus anthracis is reported. An improved synthesis utilizing a new pincer catalyst, dichlorobis[1-(dicyclohexylphosphanyl)-piperidine]palladium(II), allows the final Heck couplin...

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Detalles Bibliográficos
Autores principales:	Muddala, Nagendra Prasad, Nammalwar, Baskar, Selvaraju, Subhashini, Bourne, Christina R., Henry, Mary, Bunce, Richard A., Berlin, K. Darrell, Barrow, Esther W., Barrow, William W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445145/ https://www.ncbi.nlm.nih.gov/pubmed/25905602 http://dx.doi.org/10.3390/molecules20047222

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