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Exploring Interaction of TNF and Orthopoxviral CrmB Protein by Surface Plasmon Resonance and Free Energy Calculation

Inhibition of the activity of the tumor necrosis factor (TNF) has become the main strategy for treating inflammatory diseases. The orthopoxvirus TNF-binding proteins can bind and efficiently neutralize TNF. To analyze the mechanisms of the interaction between human (hTNF) or mouse (mTNF) TNF and the...

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Detalles Bibliográficos
Autores principales:	Ivanisenko, Nikita V., Tregubchak, Tatiana V., Saik, Olga V., Ivanisenko, Vladimir A., Shchelkunov, Sergei N.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bentham Science Publishers 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445422/ https://www.ncbi.nlm.nih.gov/pubmed/25101631 http://dx.doi.org/10.2174/0929866521666140805125322

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