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Lithospermic acid attenuates 1-methyl-4-phenylpyridine-induced neurotoxicity by blocking neuronal apoptotic and neuroinflammatory pathways

BACKGROUND: Parkinson’s disease is the second most common neurodegenerative disorders after Alzheimer’s disease. The main cause of the disease is the massive degeneration of dopaminergic neurons in the substantia nigra. Neuronal apoptosis and neuroinflammation are thought to be the key contributors...

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Detalles Bibliográficos
Autores principales: Lin, Yun-Lian, Tsay, Huey-Jen, Lai, Tzu-Hsuan, Tzeng, Tsai-Teng, Shiao, Young-Ji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445499/
https://www.ncbi.nlm.nih.gov/pubmed/26018660
http://dx.doi.org/10.1186/s12929-015-0146-y