The application of antimicrobial peptides as growth and health promoters for swine

With the widespread ban on the use of antibiotics in swine feed, alternative measures need to be sought to maintain swine health and performance. Antimicrobial peptides (AMPs) are part of the nonspecific defense system and are natural antibiotics produced by plants, insects, mammalians, and micro-or...

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Autores principales: Xiao, Hao, Shao, Fangyuan, Wu, Miaomiao, Ren, Wenkai, Xiong, Xia, Tan, Bie, Yin, Yulong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445505/
https://www.ncbi.nlm.nih.gov/pubmed/26019864
http://dx.doi.org/10.1186/s40104-015-0018-z
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author Xiao, Hao
Shao, Fangyuan
Wu, Miaomiao
Ren, Wenkai
Xiong, Xia
Tan, Bie
Yin, Yulong
author_facet Xiao, Hao
Shao, Fangyuan
Wu, Miaomiao
Ren, Wenkai
Xiong, Xia
Tan, Bie
Yin, Yulong
author_sort Xiao, Hao
collection PubMed
description With the widespread ban on the use of antibiotics in swine feed, alternative measures need to be sought to maintain swine health and performance. Antimicrobial peptides (AMPs) are part of the nonspecific defense system and are natural antibiotics produced by plants, insects, mammalians, and micro-organisms as well as by chemical synthesis. Due to their broad microbicidal activity against various fungi, bacteria and enveloped viruses, AMPs are a potential alternative to conventional antibiotics for use in swine production. This review focuses on the structure and mechanism of action of AMPs, as well as their effects on performance, immune function and intestinal health in pigs. The aim is to provide support for the application of AMPs as feed additives replacing antibiotics in swine nutrition.
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spelling pubmed-44455052015-05-28 The application of antimicrobial peptides as growth and health promoters for swine Xiao, Hao Shao, Fangyuan Wu, Miaomiao Ren, Wenkai Xiong, Xia Tan, Bie Yin, Yulong J Anim Sci Biotechnol Review With the widespread ban on the use of antibiotics in swine feed, alternative measures need to be sought to maintain swine health and performance. Antimicrobial peptides (AMPs) are part of the nonspecific defense system and are natural antibiotics produced by plants, insects, mammalians, and micro-organisms as well as by chemical synthesis. Due to their broad microbicidal activity against various fungi, bacteria and enveloped viruses, AMPs are a potential alternative to conventional antibiotics for use in swine production. This review focuses on the structure and mechanism of action of AMPs, as well as their effects on performance, immune function and intestinal health in pigs. The aim is to provide support for the application of AMPs as feed additives replacing antibiotics in swine nutrition. BioMed Central 2015-05-07 /pmc/articles/PMC4445505/ /pubmed/26019864 http://dx.doi.org/10.1186/s40104-015-0018-z Text en © Xiao et al.; licensee BioMed Central. 2015 This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Review
Xiao, Hao
Shao, Fangyuan
Wu, Miaomiao
Ren, Wenkai
Xiong, Xia
Tan, Bie
Yin, Yulong
The application of antimicrobial peptides as growth and health promoters for swine
title The application of antimicrobial peptides as growth and health promoters for swine
title_full The application of antimicrobial peptides as growth and health promoters for swine
title_fullStr The application of antimicrobial peptides as growth and health promoters for swine
title_full_unstemmed The application of antimicrobial peptides as growth and health promoters for swine
title_short The application of antimicrobial peptides as growth and health promoters for swine
title_sort application of antimicrobial peptides as growth and health promoters for swine
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445505/
https://www.ncbi.nlm.nih.gov/pubmed/26019864
http://dx.doi.org/10.1186/s40104-015-0018-z
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