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Ototoxicity-induced loss of hearing and inner hair cells is attenuated by HSP70 gene transfer
The most common reason for sensorineural deafness is death of hair cells (HCs). Heat shock proteins (HSPs) are molecular chaperones that participate in folding, targeting, and degrading proteins. HSP expression is increased in response to various environmental stresses to protect cells from damage....
Autores principales: | Takada, Yohei, Takada, Tomoko, Lee, Min Young, Swiderski, Donald L, Kabara, Lisa L, Dolan, David F, Raphael, Yehoash |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445521/ https://www.ncbi.nlm.nih.gov/pubmed/26029729 http://dx.doi.org/10.1038/mtm.2015.19 |
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