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SIRT1 protects rat lung tissue against severe burn-induced remote ALI by attenuating the apoptosis of PMVECs via p38 MAPK signaling

Silent information regulator type-1 (SIRT1) has been reported to be involved in the cardiopulmonary protection. However, its role in the pathogenesis of burn-induced remote acute lung injury (ALI) is currently unknown. The present study aims to investigate the role of SIRT1 in burn-induced remote AL...

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Detalles Bibliográficos
Autores principales: Bai, Xiaozhi, Fan, Lei, He, Ting, Jia, Wenbin, Yang, Longlong, Zhang, Jun, Liu, Yang, Shi, Jihong, Su, Linlin, Hu, Dahai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445725/
https://www.ncbi.nlm.nih.gov/pubmed/25992481
http://dx.doi.org/10.1038/srep10277