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Single amino acid substitution (G42E) in the receptor binding domain of mouse mammary tumour virus envelope protein facilitates infection of non-murine cells in a transferrin receptor 1-independent manner

BACKGROUND: Mouse mammary tumour virus (MMTV) is a betaretrovirus that infects rodent cells and uses mouse tranferrin receptor 1 (TfR1) for cell entry. Several MMTV strains have been shown to productively infect, in addition to murine cells, various heterologous cell lines including those of human o...

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Detalles Bibliográficos
Autores principales:	Konstantoulas, Constantine James, Lamp, Benjamin, Rumenapf, Tillman Hans, Indik, Stanislav
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445801/ https://www.ncbi.nlm.nih.gov/pubmed/25980759 http://dx.doi.org/10.1186/s12977-015-0168-2

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