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Low expression levels of hepsin and TMPRSS3 are associated with poor breast cancer survival

BACKGROUND: Hepsin, (also called TMPRSS1) and TMPRSS3 are type II transmembrane serine proteases (TTSPs) that are involved in cancer progression. TTSPs can remodel extracellular matrix (ECM) and, when dysregulated, promote tumor progression and metastasis by inducing defects in basement membrane and...

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Detalles Bibliográficos
Autores principales:	Pelkonen, Mikko, Luostari, Kaisa, Tengström, Maria, Ahonen, Hermanni, Berdel, Bozena, Kataja, Vesa, Soini, Ylermi, Kosma, Veli-Matti, Mannermaa, Arto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445813/ https://www.ncbi.nlm.nih.gov/pubmed/26014348 http://dx.doi.org/10.1186/s12885-015-1440-5

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