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Detection of Cytosine Methylation in Ancient DNA from Five Native American Populations Using Bisulfite Sequencing
While cytosine methylation has been widely studied in extant populations, relatively few studies have analyzed methylation in ancient DNA. Most existing studies of epigenetic marks in ancient DNA have inferred patterns of methylation in highly degraded samples using post-mortem damage to cytosines a...
Autores principales: | Smith, Rick W. A., Monroe, Cara, Bolnick, Deborah A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4445908/ https://www.ncbi.nlm.nih.gov/pubmed/26016479 http://dx.doi.org/10.1371/journal.pone.0125344 |
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