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Anti-Inflammatory Action of an Antimicrobial Model Peptide That Suppresses the TRIF-Dependent Signaling Pathway via Inhibition of Toll-Like Receptor 4 Endocytosis in Lipopolysaccharide-Stimulated Macrophages
Antimicrobial peptides (AMPs), also called host defense peptides, particularly those with amphipathic helical structures, are emerging as target molecules for therapeutic development due to their immunomodulatory properties. Although the antimicrobial activity of AMPs is known to be exerted primaril...
Autores principales: | Shim, Do-Wan, Heo, Kang-Hyuck, Kim, Young-Kyu, Sim, Eun-Jeong, Kang, Tae-Bong, Choi, Jae-Wan, Sim, Dae-Won, Cheong, Sun-Hee, Lee, Seung-Hong, Bang, Jeong-Kyu, Won, Hyung-Sik, Lee, Kwang-Ho |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446091/ https://www.ncbi.nlm.nih.gov/pubmed/26017270 http://dx.doi.org/10.1371/journal.pone.0126871 |
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