(90)Y-Labeled Anti-ROBO1 Monoclonal Antibody Exhibits Antitumor Activity against Small Cell Lung Cancer Xenografts

INTRODUCTION: ROBO1 is a membrane protein that contributes to tumor metastasis and angiogenesis. We previously reported that (90)Y-labeled anti-ROBO1 monoclonal antibody ((90)Y-anti-ROBO1 IgG) showed an antitumor effect against ROBO1-positive tumors. In this study, we performed a biodistribution stu...

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Detalles Bibliográficos
Autores principales: Fujiwara, Kentaro, Koyama, Keitaro, Suga, Kosuke, Ikemura, Masako, Saito, Yasutaka, Hino, Akihiro, Iwanari, Hiroko, Kusano-Arai, Osamu, Mitsui, Kenichi, Kasahara, Hiroyuki, Fukayama, Masashi, Kodama, Tatsuhiko, Hamakubo, Takao, Momose, Toshimitsu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446100/
https://www.ncbi.nlm.nih.gov/pubmed/26017283
http://dx.doi.org/10.1371/journal.pone.0125468

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