Activation of Notch1 signalling promotes multi-lineage differentiation of c-Kit(POS)/NKX2.5(POS) bone marrow stem cells: implication in stem cell translational medicine

INTRODUCTION: Transplantation of bone marrow mesenchymal stem cells (BMSCs) can repair injured hearts. However, whether BMSC populations contain cells with cardiac stem cell characteristics is ill-defined. We report here that Notch signalling can promote differentiation of c-Kit(POS)/NKX2.5(POS) BMS...

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Detalles Bibliográficos
Autores principales: Ding, Ranran, Jiang, Xiaofan, Ha, Yanping, Wang, Zhenliang, Guo, Junli, Jiang, Hanguo, Zheng, Shaojiang, Shen, Zhihua, Jie, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446115/
https://www.ncbi.nlm.nih.gov/pubmed/25956503
http://dx.doi.org/10.1186/s13287-015-0085-2

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