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A neural basis for melanocortin-4 receptor regulated appetite

Pro-opiomelanocortin (POMC)- and agouti-related peptide (AgRP)-expressing neurons are oppositely regulated by caloric depletion and co-ordinately stimulate and inhibit homeostatic satiety, respectively. This bimodality is principally underscored by the antagonistic actions of these ligands at downst...

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Detalles Bibliográficos
Autores principales: Garfield, Alastair S., Li, Chia, Madara, Joseph C., Shah, Bhavik P., Webber, Emily, Steger, Jennifer S., Campbell, John N., Gavrilova, Oksana, Lee, Charlotte E., Olson, David P., Elmquist, Joel K., Tannous, Bakhos A., Krashes, Michael J., Lowell, Bradford B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446192/
https://www.ncbi.nlm.nih.gov/pubmed/25915476
http://dx.doi.org/10.1038/nn.4011