Cargando…
A neural basis for melanocortin-4 receptor regulated appetite
Pro-opiomelanocortin (POMC)- and agouti-related peptide (AgRP)-expressing neurons are oppositely regulated by caloric depletion and co-ordinately stimulate and inhibit homeostatic satiety, respectively. This bimodality is principally underscored by the antagonistic actions of these ligands at downst...
Autores principales: | Garfield, Alastair S., Li, Chia, Madara, Joseph C., Shah, Bhavik P., Webber, Emily, Steger, Jennifer S., Campbell, John N., Gavrilova, Oksana, Lee, Charlotte E., Olson, David P., Elmquist, Joel K., Tannous, Bakhos A., Krashes, Michael J., Lowell, Bradford B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446192/ https://www.ncbi.nlm.nih.gov/pubmed/25915476 http://dx.doi.org/10.1038/nn.4011 |
Ejemplares similares
-
Dynamic GABAergic afferent modulation of AgRP neurons
por: Garfield, Alastair S, et al.
Publicado: (2016) -
Melanocortin 4 receptors in autonomic neurons regulate thermogenesis and glycemia
por: Berglund, Eric D., et al.
Publicado: (2014) -
A Novel Excitatory Paraventricular Nucleus to AgRP Neuron Circuit that Drives Hunger
por: Krashes, Michael J., et al.
Publicado: (2014) -
Current Mechanistic and Pharmacodynamic Understanding of Melanocortin-4 Receptor Activation
por: Sharma, Shubh, et al.
Publicado: (2019) -
Melanocortin regulation of histaminergic neurons via perifornical lateral hypothalamic melanocortin 4 receptors
por: Michael, Natalie J., et al.
Publicado: (2020)