Death of Neurons following Injury Requires Conductive Neuronal Gap Junction Channels but Not a Specific Connexin

Pharmacological blockade or genetic knockout of neuronal connexin 36 (Cx36)-containing gap junctions reduces neuronal death caused by ischemia, traumatic brain injury and NMDA receptor (NMDAR)-mediated excitotoxicity. However, whether Cx36 gap junctions contribute to neuronal death via channel-depen...

Descripción completa

Detalles Bibliográficos
Autores principales: Fontes, Joseph D., Ramsey, Jon, Polk, Jeremy M, Koop, Andre, Denisova, Janna V., Belousov, Andrei B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446213/
https://www.ncbi.nlm.nih.gov/pubmed/26017008
http://dx.doi.org/10.1371/journal.pone.0125395

Ejemplares similares

Ejemplares similares