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Impaired M. tuberculosis Antigen-Specific IFN-γ Response without IL-17 Enhancement in Patients with Severe Cavitary Pulmonary Tuberculosis

BACKGROUND: Th1 cells play an essential role in immune protection against tuberculosis. Th17 cells might be involved with immune pathology in active human tuberculosis (TB). The balance between Th1 and Th17 cells in patients with cavitary tuberculosis needs to be clarified which might help understan...

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Detalles Bibliográficos
Autores principales: Fan, Lin, Xiao, Heping, Mai, Guangliang, Su, Bo, Ernst, Joel, Hu, Zhongyi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446217/
https://www.ncbi.nlm.nih.gov/pubmed/26018190
http://dx.doi.org/10.1371/journal.pone.0127087