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Structure-Activity Relationships for the Antifungal Activity of Selective Estrogen Receptor Antagonists Related to Tamoxifen

Cryptococcosis is one of the most important invasive fungal infections and is a significant contributor to the mortality associated with HIV/AIDS. As part of our program to repurpose molecules related to the selective estrogen receptor modulator (SERM) tamoxifen as anti-cryptococcal agents, we have...

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Detalles Bibliográficos
Autores principales: Butts, Arielle, Martin, Jennifer A., DiDone, Louis, Bradley, Erin K., Mutz, Mitchell, Krysan, Damian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446328/
https://www.ncbi.nlm.nih.gov/pubmed/26016941
http://dx.doi.org/10.1371/journal.pone.0125927