Mitochondrial Dysfunction in Human Leukemic Stem/Progenitor Cells upon Loss of RAC2

Leukemic stem cells (LSCs) reside within bone marrow niches that maintain their relatively quiescent state and convey resistance to conventional treatment. Many of the microenvironmental signals converge on RAC GTPases. Although it has become clear that RAC proteins fulfill important roles in the he...

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Detalles Bibliográficos
Autores principales: Capala, Marta E., Maat, Henny, Bonardi, Francesco, van den Boom, Vincent, Kuipers, Jeroen, Vellenga, Edo, Giepmans, Ben N. G., Schuringa, Jan Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446344/
https://www.ncbi.nlm.nih.gov/pubmed/26016997
http://dx.doi.org/10.1371/journal.pone.0128585

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446344/
https://www.ncbi.nlm.nih.gov/pubmed/26016997
http://dx.doi.org/10.1371/journal.pone.0128585

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