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Argonaute of the archaeon Pyrococcus furiosus is a DNA-guided nuclease that targets cognate DNA

Functions of prokaryotic Argonautes (pAgo) have long remained elusive. Recently, Argonautes of the bacteria Rhodobacter sphaeroides and Thermus thermophilus were demonstrated to be involved in host defense. The Argonaute of the archaeon Pyrococcus furiosus (PfAgo) belongs to a different branch in th...

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Detalles Bibliográficos
Autores principales:	Swarts, Daan C., Hegge, Jorrit W., Hinojo, Ismael, Shiimori, Masami, Ellis, Michael A., Dumrongkulraksa, Justin, Terns, Rebecca M., Terns, Michael P., van der Oost, John
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2015
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446448/ https://www.ncbi.nlm.nih.gov/pubmed/25925567 http://dx.doi.org/10.1093/nar/gkv415

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