Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla

Dereplication and chemotaxonomic studies of six marine algae of the Ochrophyta and one of the Rhodophyta phyla resulted in the detection of 22 separate compounds. All 16 secondary metabolites, including four new compounds (16–19), could be rapidly dereplicated using HPLC-NMR and HPLC-MS methodologie...

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Autores principales: Brkljača, Robert, Gӧker, Emrehan Semih, Urban, Sylvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446602/
https://www.ncbi.nlm.nih.gov/pubmed/25942092
http://dx.doi.org/10.3390/md13052714
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author Brkljača, Robert
Gӧker, Emrehan Semih
Urban, Sylvia
author_facet Brkljača, Robert
Gӧker, Emrehan Semih
Urban, Sylvia
author_sort Brkljača, Robert
collection PubMed
description Dereplication and chemotaxonomic studies of six marine algae of the Ochrophyta and one of the Rhodophyta phyla resulted in the detection of 22 separate compounds. All 16 secondary metabolites, including four new compounds (16–19), could be rapidly dereplicated using HPLC-NMR and HPLC-MS methodologies in conjunction with the MarinLit database. This study highlights the advantages of using NMR data (acquired via HPLC-NMR) for database searching and for the overall dereplication of natural products.
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spelling pubmed-44466022015-05-29 Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla Brkljača, Robert Gӧker, Emrehan Semih Urban, Sylvia Mar Drugs Article Dereplication and chemotaxonomic studies of six marine algae of the Ochrophyta and one of the Rhodophyta phyla resulted in the detection of 22 separate compounds. All 16 secondary metabolites, including four new compounds (16–19), could be rapidly dereplicated using HPLC-NMR and HPLC-MS methodologies in conjunction with the MarinLit database. This study highlights the advantages of using NMR data (acquired via HPLC-NMR) for database searching and for the overall dereplication of natural products. MDPI 2015-04-30 /pmc/articles/PMC4446602/ /pubmed/25942092 http://dx.doi.org/10.3390/md13052714 Text en © 2015 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Brkljača, Robert
Gӧker, Emrehan Semih
Urban, Sylvia
Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla
title Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla
title_full Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla
title_fullStr Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla
title_full_unstemmed Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla
title_short Dereplication and Chemotaxonomical Studies of Marine Algae of the Ochrophyta and Rhodophyta Phyla
title_sort dereplication and chemotaxonomical studies of marine algae of the ochrophyta and rhodophyta phyla
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446602/
https://www.ncbi.nlm.nih.gov/pubmed/25942092
http://dx.doi.org/10.3390/md13052714
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