Activating MET Kinase Rearrangements in Melanoma and Spitz Tumors

Oncogenic gene fusions have been identified in many cancers and many serve as biomarkers or targets for therapy. Here we identify six different melanocytic tumors with genomic rearrangements of MET fusing the kinase domain of MET in-frame to six different N-terminal partners. These tumors lack activ...

Descripción completa

Detalles Bibliográficos
Autores principales: Yeh, Iwei, Botton, Thomas, Talevich, Eric, Shain, A. Hunter, Sparatta, Alyssa J., de la Fouchardiere, Arnaud, Mully, Thaddeus W., North, Jeffrey P., Garrido, Maria C., Gagnon, Alexander, Vemula, Swapna S., McCalmont, Timothy H., LeBoit, Philip E., Bastian, Boris C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446791/
https://www.ncbi.nlm.nih.gov/pubmed/26013381
http://dx.doi.org/10.1038/ncomms8174

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446791/
https://www.ncbi.nlm.nih.gov/pubmed/26013381
http://dx.doi.org/10.1038/ncomms8174

Ejemplares similares