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Metabolic changes in type 2 diabetes are reflected in peripheral blood cells, revealing aberrant cytotoxicity, a viral signature, and hypoxia inducible factor activity
BACKGROUND: Metabolic syndrome (MetS) is characterized by central obesity, insulin resistance, dysglycemia, and a pro-atherogenic plasma lipid profile. MetS creates a high risk for development of type 2 diabetes (T2DM) and cardiovascular disease (CVD), presumably by altering inflammatory responses....
Autores principales: | van der Pouw Kraan, Tineke C. T. M., Chen, Weena J., Bunck, Mathijs C. M., van Raalte, Daniel H., van der Zijl, Nynke J., van Genugten, Renate E., van Bloemendaal, Liselotte, Baggen, Josefien M., Serné, Erik H., Diamant, Michaela, Horrevoets, Anton J. G. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4446948/ https://www.ncbi.nlm.nih.gov/pubmed/25956355 http://dx.doi.org/10.1186/s12920-015-0096-y |
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