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COSMC knockdown mediated aberrant O-glycosylation promotes oncogenic properties in pancreatic cancer

BACKGROUND: Human pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and lethal malignancies in the world and despite great efforts in research types of treatment remain limited. A frequently detected alteration in PDACs is a truncated O-linked N-acetylgalactosamine (GalNAc) glyco...

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Detalles Bibliográficos
Autores principales:	Hofmann, Bianca T., Schlüter, Laura, Lange, Philip, Mercanoglu, Baris, Ewald, Florian, Fölster, Aljonna, Picksak, Aeint-Steffen, Harder, Sönke, El Gammal, Alexander T., Grupp, Katharina, Güngör, Cenap, Drenckhan, Astrid, Schlüter, Hartmut, Wagener, Christoph, Izbicki, Jakob R., Jücker, Manfred, Bockhorn, Maximilian, Wolters-Eisfeld, Gerrit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447007/ https://www.ncbi.nlm.nih.gov/pubmed/26021314 http://dx.doi.org/10.1186/s12943-015-0386-1

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