Insulin stimulates SGLT2-mediated tubular glucose absorption via oxidative stress generation

BACKGROUND: Ninety percent of glucose filtered by the glomerulus is reabsorbed by a sodium-glucose cotransporter 2 (SGLT2), which is expressed mainly on the apical membrane of renal proximal tubules. Since SGLT-2-mediated glucose reabsorption is enhanced under diabetic conditions, selective inhibiti...

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Detalles Bibliográficos
Autores principales: Nakamura, Nobutaka, Matsui, Takanori, Ishibashi, Yuji, Yamagishi, Sho-ichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447012/
https://www.ncbi.nlm.nih.gov/pubmed/26023321
http://dx.doi.org/10.1186/s13098-015-0044-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447012/
https://www.ncbi.nlm.nih.gov/pubmed/26023321
http://dx.doi.org/10.1186/s13098-015-0044-1

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