Advances in the understanding and management of heart transplantation

Cardiac transplantation represents one of the great triumphs in modern medicine and remains the cornerstone in the treatment of advanced heart failure. In this review, we contextualize pivotal developments in our understanding and management of cardiac transplant immunology, histopathology, rejectio...

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Detalles Bibliográficos
Autores principales: Singh, Dhssraj, Taylor, David O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty of 1000 Ltd 2015
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447052/
https://www.ncbi.nlm.nih.gov/pubmed/26097725
http://dx.doi.org/10.12703/P7-52
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author Singh, Dhssraj
Taylor, David O.
author_facet Singh, Dhssraj
Taylor, David O.
author_sort Singh, Dhssraj
collection PubMed
description Cardiac transplantation represents one of the great triumphs in modern medicine and remains the cornerstone in the treatment of advanced heart failure. In this review, we contextualize pivotal developments in our understanding and management of cardiac transplant immunology, histopathology, rejection surveillance, drug development and surgery. We also discuss current limitations in their application and the impact of the left ventricular assist devices in bridging this gap.
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spelling pubmed-44470522015-06-19 Advances in the understanding and management of heart transplantation Singh, Dhssraj Taylor, David O. F1000Prime Rep Review Article Cardiac transplantation represents one of the great triumphs in modern medicine and remains the cornerstone in the treatment of advanced heart failure. In this review, we contextualize pivotal developments in our understanding and management of cardiac transplant immunology, histopathology, rejection surveillance, drug development and surgery. We also discuss current limitations in their application and the impact of the left ventricular assist devices in bridging this gap. Faculty of 1000 Ltd 2015-05-12 /pmc/articles/PMC4447052/ /pubmed/26097725 http://dx.doi.org/10.12703/P7-52 Text en © 2015 Faculty of 1000 Ltd http://creativecommons.org/licenses/by-nc/3.0/legalcode All F1000Prime Reports articles are distributed under the terms of the Creative Commons Attribution-Non Commercial License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Singh, Dhssraj
Taylor, David O.
Advances in the understanding and management of heart transplantation
title Advances in the understanding and management of heart transplantation
title_full Advances in the understanding and management of heart transplantation
title_fullStr Advances in the understanding and management of heart transplantation
title_full_unstemmed Advances in the understanding and management of heart transplantation
title_short Advances in the understanding and management of heart transplantation
title_sort advances in the understanding and management of heart transplantation
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447052/
https://www.ncbi.nlm.nih.gov/pubmed/26097725
http://dx.doi.org/10.12703/P7-52
work_keys_str_mv AT singhdhssraj advancesintheunderstandingandmanagementofhearttransplantation
AT taylordavido advancesintheunderstandingandmanagementofhearttransplantation

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