GABA(B) receptor upregulates fragile X mental retardation protein expression in neurons

Fragile X mental retardation protein (FMRP) is an RNA-binding protein important for the control of translation and synaptic function. The mutation or silencing of FMRP causes Fragile X syndrome (FXS), which leads to intellectual disability and social impairment. γ-aminobutyric acid (GABA) is the maj...

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Detalles Bibliográficos
Autores principales: Zhang, Wenhua, Xu, Chanjuan, Tu, Haijun, Wang, Yunyun, Sun, Qian, Hu, Ping, Hu, Yongjian, Rondard, Philippe, Liu, Jianfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447080/
https://www.ncbi.nlm.nih.gov/pubmed/26020477
http://dx.doi.org/10.1038/srep10468

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