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Design Space Development for the Extraction Process of Danhong Injection Using a Monte Carlo Simulation Method
A design space approach was applied to optimize the extraction process of Danhong injection. Dry matter yield and the yields of five active ingredients were selected as process critical quality attributes (CQAs). Extraction number, extraction time, and the mass ratio of water and material (W/M ratio...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447344/ https://www.ncbi.nlm.nih.gov/pubmed/26020778 http://dx.doi.org/10.1371/journal.pone.0128236 |