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The Drosophila Insulin Receptor Independently Modulates Lifespan and Locomotor Senescence

The Insulin/IGF-like signalling (IIS) pathway plays an evolutionarily conserved role in ageing. In model organisms reduced IIS extends lifespan and ameliorates some forms of functional senescence. However, little is known about IIS in nervous system ageing and behavioural senescence. To investigate...

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Detalles Bibliográficos
Autores principales:	Ismail, Mohd Zamri Bin Haji, Hodges, Matt D., Boylan, Michael, Achall, Rajesh, Shirras, Alan, Broughton, Susan J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447345/ https://www.ncbi.nlm.nih.gov/pubmed/26020640 http://dx.doi.org/10.1371/journal.pone.0125312

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