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Disruption of miR-29 Leads to Aberrant Differentiation of Smooth Muscle Cells Selectively Associated with Distal Lung Vasculature
Differentiation of lung vascular smooth muscle cells (vSMCs) is tightly regulated during development or in response to challenges in a vessel specific manner. Aberrant vSMCs specifically associated with distal pulmonary arteries have been implicated in the pathogenesis of respiratory diseases, such...
Autores principales: | Cushing, Leah, Costinean, Stefan, Xu, Wei, Jiang, Zhihua, Madden, Lindsey, Kuang, Pingping, Huang, Jingshu, Weisman, Alexandra, Hata, Akiko, Croce, Carlo M., Lü, Jining |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447351/ https://www.ncbi.nlm.nih.gov/pubmed/26020233 http://dx.doi.org/10.1371/journal.pgen.1005238 |
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