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β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates

Continuous taste bud cell renewal is essential to maintain taste function in adults; however, the molecular mechanisms that regulate taste cell turnover are unknown. Using inducible Cre-lox technology, we show that activation of β-catenin signaling in multipotent lingual epithelial progenitors outsi...

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Detalles Bibliográficos
Autores principales: Gaillard, Dany, Xu, Mingang, Liu, Fei, Millar, Sarah E., Barlow, Linda A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447363/
https://www.ncbi.nlm.nih.gov/pubmed/26020789
http://dx.doi.org/10.1371/journal.pgen.1005208