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β-Catenin Signaling Biases Multipotent Lingual Epithelial Progenitors to Differentiate and Acquire Specific Taste Cell Fates
Continuous taste bud cell renewal is essential to maintain taste function in adults; however, the molecular mechanisms that regulate taste cell turnover are unknown. Using inducible Cre-lox technology, we show that activation of β-catenin signaling in multipotent lingual epithelial progenitors outsi...
Autores principales: | Gaillard, Dany, Xu, Mingang, Liu, Fei, Millar, Sarah E., Barlow, Linda A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447363/ https://www.ncbi.nlm.nih.gov/pubmed/26020789 http://dx.doi.org/10.1371/journal.pgen.1005208 |
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