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Ketamine Causes Mitochondrial Dysfunction in Human Induced Pluripotent Stem Cell-Derived Neurons

PURPOSE: Ketamine toxicity has been demonstrated in nonhuman mammalian neurons. To study the toxic effect of ketamine on human neurons, an experimental model of cultured neurons from human induced pluripotent stem cells (iPSCs) was examined, and the mechanism of its toxicity was investigated. METHOD...

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Detalles Bibliográficos
Autores principales:	Ito, Hiroyuki, Uchida, Tokujiro, Makita, Koshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447382/ https://www.ncbi.nlm.nih.gov/pubmed/26020236 http://dx.doi.org/10.1371/journal.pone.0128445

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