Macrophage Migration Inhibitory Factor Mediates PAR-Induced Bladder Pain

INTRODUCTION: Macrophage migration inhibitory factor (MIF), a pro-inflammatory cytokine, is constitutively expressed in urothelial cells that also express protease-activated receptors (PAR). Urothelial PAR1 receptors were shown to mediate bladder inflammation. We showed that PAR1 and PAR4 activator,...

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Detalles Bibliográficos
Autores principales: Kouzoukas, Dimitrios E., Meyer-Siegler, Katherine L., Ma, Fei, Westlund, Karin N., Hunt, David E., Vera, Pedro L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447427/
https://www.ncbi.nlm.nih.gov/pubmed/26020638
http://dx.doi.org/10.1371/journal.pone.0127628

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