Abbreviated Exposure to Hypoxia Is Sufficient to Induce CNS Dysmyelination, Modulate Spinal Motor Neuron Composition, and Impair Motor Development in Neonatal Mice

Neonatal white matter injury (nWMI) is an increasingly common cause of cerebral palsy that results predominantly from hypoxic injury to progenitor cells including those of the oligodendrocyte lineage. Existing mouse models of nWMI utilize prolonged periods of hypoxia during the neonatal period, requ...

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Detalles Bibliográficos
Autores principales: Watzlawik, Jens O., Kahoud, Robert J., O’Toole, Ryan J., White, Katherine A. M., Ogden, Alyssa R., Painter, Meghan M., Wootla, Bharath, Papke, Louisa M., Denic, Aleksandar, Weimer, Jill M., Carey, William A., Rodriguez, Moses
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447462/
https://www.ncbi.nlm.nih.gov/pubmed/26020269
http://dx.doi.org/10.1371/journal.pone.0128007

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