Progressive Impairment of Lactate-based Gluconeogenesis in the Huntington’s Disease Mouse Model R6/2

Huntington’s disease (HD) is a neurodegenerative illness, where selective neuronal loss in the brain caused by expression of mutant huntingtin protein leads to motor dysfunction and cognitive decline in addition to peripheral metabolic changes. In this study we confirm our previous observation of im...

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Detalles Bibliográficos
Autores principales: Nielsen, Signe Marie Borch, Hasholt, Lis, Nørremølle, Anne, Josefsen, Knud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447482/
https://www.ncbi.nlm.nih.gov/pubmed/26064782
http://dx.doi.org/10.1371/currents.hd.019b33aae1c519e6e8b68e7cf3e7818e

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447482/
https://www.ncbi.nlm.nih.gov/pubmed/26064782
http://dx.doi.org/10.1371/currents.hd.019b33aae1c519e6e8b68e7cf3e7818e

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