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Progressive Impairment of Lactate-based Gluconeogenesis in the Huntington’s Disease Mouse Model R6/2
Huntington’s disease (HD) is a neurodegenerative illness, where selective neuronal loss in the brain caused by expression of mutant huntingtin protein leads to motor dysfunction and cognitive decline in addition to peripheral metabolic changes. In this study we confirm our previous observation of im...
Autores principales: | Nielsen, Signe Marie Borch, Hasholt, Lis, Nørremølle, Anne, Josefsen, Knud |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447482/ https://www.ncbi.nlm.nih.gov/pubmed/26064782 http://dx.doi.org/10.1371/currents.hd.019b33aae1c519e6e8b68e7cf3e7818e |
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