Cargando…
Development and Characterization of Human Induced Pluripotent Stem Cell-Derived Cholangiocytes
BACKGROUND AND AIMS: Cholangiocytes are the target of a heterogeneous group of liver diseases, known as the cholangiopathies. An evolving understanding of the mechanisms driving biliary development provides the theoretical underpinnings for rational development of induced pluripotent stem cell (iPSC...
Autores principales: | De Assuncao, Thiago M., Sun, Yan, Jalan-Sakrikar, Nidhi, Drinane, Mary, Huang, Bing Q., Li, Ying, Davila, Jaime I., Wang, Ruisi, O’Hara, Steven P., Lomberk, Gwen A., Urrutia, Raul A., Ikeda, Yasuhiro, Huebert, Robert C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447567/ https://www.ncbi.nlm.nih.gov/pubmed/25867762 http://dx.doi.org/10.1038/labinvest.2015.51 |
Ejemplares similares
-
Hedgehog Signaling Overcomes an EZH2-Dependent Epigenetic Barrier to Promote Cholangiocyte Expansion
por: Jalan-Sakrikar, Nidhi, et al.
Publicado: (2016) -
Telomere dysfunction promotes cholangiocyte senescence and biliary fibrosis in primary sclerosing cholangitis
por: Jalan-Sakrikar, Nidhi, et al.
Publicado: (2023) -
Development and Characterization of Cholangioids from Normal and Diseased Human Cholangiocytes as an In Vitro Model to Study Primary Sclerosing Cholangitis
por: Loarca, Lorena, et al.
Publicado: (2017) -
Enhancer of Zeste Homologue 2 Inhibition Attenuates TGF-β Dependent Hepatic Stellate Cell Activation and Liver Fibrosis
por: Martin-Mateos, Rosa, et al.
Publicado: (2018) -
Induced Pluripotent Stem Cells From Subjects With Primary Sclerosing Cholangitis Develop a Senescence Phenotype Following Biliary Differentiation
por: Jalan‐Sakrikar, Nidhi, et al.
Publicado: (2021)