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The ClpS-like N-domain is essential for the functioning of Ubr11, an N-recognin in Schizosaccharomyces pombe
Several Ubr ubiquitin ligases recognize the N-terminal amino acid of substrate proteins and promote their degradation via the Arg/N-end rule pathway. The primary destabilizing N-terminal amino acids in yeast are classified into type 1 (Arg, Lys, and His) and type 2 (Phe, Trp, Tyr, Leu, Ile, and Met-...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer International Publishing
2014
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4447728/ https://www.ncbi.nlm.nih.gov/pubmed/26034658 http://dx.doi.org/10.1186/2193-1801-3-257 |