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The CXCL12/CXCR4 Axis Plays a Critical Role in Coronary Artery Development
The chemokine CXCL12 and its receptor CXCR4 have many functions during embryonic and post-natal life. We used murine models to investigate the role of CXCL12/CXCR4 signaling in cardiac development and found that embryonic Cxcl12-null hearts lacked intra-ventricular coronary arteries (CAs) and exhibi...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Cell Press
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448146/ https://www.ncbi.nlm.nih.gov/pubmed/26017770 http://dx.doi.org/10.1016/j.devcel.2015.03.026 |