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In Vivo Imaging Reveals Extracellular Vesicle-Mediated Phenocopying of Metastatic Behavior

Most cancer cells release heterogeneous populations of extracellular vesicles (EVs) containing proteins, lipids, and nucleic acids. In vitro experiments showed that EV uptake can lead to transfer of functional mRNA and altered cellular behavior. However, similar in vivo experiments remain challengin...

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Detalles Bibliográficos
Autores principales: Zomer, Anoek, Maynard, Carrie, Verweij, Frederik Johannes, Kamermans, Alwin, Schäfer, Ronny, Beerling, Evelyne, Schiffelers, Raymond Michel, de Wit, Elzo, Berenguer, Jordi, Ellenbroek, Saskia Inge Johanna, Wurdinger, Thomas, Pegtel, Dirk Michiel, van Rheenen, Jacco
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448148/
https://www.ncbi.nlm.nih.gov/pubmed/26000481
http://dx.doi.org/10.1016/j.cell.2015.04.042