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Signal detection analysis of blindsight in monkeys

Macaque monkeys with a unilateral lesion in V1 have been used as an animal model of blindsight. While objective proof of blindsight requires that the two aspects of blindsight (residual forced-choice localization and attenuated yes-no detection) should be tested under identical stimulus conditions u...

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Autores principales: Yoshida, Masatoshi, Isa, Tadashi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448228/
https://www.ncbi.nlm.nih.gov/pubmed/26021856
http://dx.doi.org/10.1038/srep10755
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author Yoshida, Masatoshi
Isa, Tadashi
author_facet Yoshida, Masatoshi
Isa, Tadashi
author_sort Yoshida, Masatoshi
collection PubMed
description Macaque monkeys with a unilateral lesion in V1 have been used as an animal model of blindsight. While objective proof of blindsight requires that the two aspects of blindsight (residual forced-choice localization and attenuated yes-no detection) should be tested under identical stimulus conditions using bias-free measures of sensitivity, these have not been attained in studies of nonhuman primates. Here we tested two macaque monkeys with a unilateral V1 lesion with two saccade tasks using identical stimuli: a forced-choice (FC) task and a yes-no (YN) task. An analysis based on signal detection theory revealed that sensitivity in the FC task was significantly higher than that in the YN task. Such dissociation of sensitivity between the two tasks was not observed when near-threshold visual stimuli were presented in the normal, unaffected hemifield. These results suggest that the V1-lesioned monkeys resemble the well-studied blindsight patient G.Y., whose visual experience per se was completely abolished.
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spelling pubmed-44482282015-06-10 Signal detection analysis of blindsight in monkeys Yoshida, Masatoshi Isa, Tadashi Sci Rep Article Macaque monkeys with a unilateral lesion in V1 have been used as an animal model of blindsight. While objective proof of blindsight requires that the two aspects of blindsight (residual forced-choice localization and attenuated yes-no detection) should be tested under identical stimulus conditions using bias-free measures of sensitivity, these have not been attained in studies of nonhuman primates. Here we tested two macaque monkeys with a unilateral V1 lesion with two saccade tasks using identical stimuli: a forced-choice (FC) task and a yes-no (YN) task. An analysis based on signal detection theory revealed that sensitivity in the FC task was significantly higher than that in the YN task. Such dissociation of sensitivity between the two tasks was not observed when near-threshold visual stimuli were presented in the normal, unaffected hemifield. These results suggest that the V1-lesioned monkeys resemble the well-studied blindsight patient G.Y., whose visual experience per se was completely abolished. Nature Publishing Group 2015-05-29 /pmc/articles/PMC4448228/ /pubmed/26021856 http://dx.doi.org/10.1038/srep10755 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Yoshida, Masatoshi
Isa, Tadashi
Signal detection analysis of blindsight in monkeys
title Signal detection analysis of blindsight in monkeys
title_full Signal detection analysis of blindsight in monkeys
title_fullStr Signal detection analysis of blindsight in monkeys
title_full_unstemmed Signal detection analysis of blindsight in monkeys
title_short Signal detection analysis of blindsight in monkeys
title_sort signal detection analysis of blindsight in monkeys
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448228/
https://www.ncbi.nlm.nih.gov/pubmed/26021856
http://dx.doi.org/10.1038/srep10755
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