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Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

INTRODUCTION: A major subset of patients with rheumatoid arthritis (RA) is characterized by the presence of circulating autoantibodies directed to citrullinated proteins/peptides (ACPAs). These autoantibodies, which are commonly detected by using an enzyme-linked immunosorbent assay (ELISA) based on...

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Detalles Bibliográficos
Autores principales: Ossipova, Elena, Cerqueira, Cátia Fernandes, Reed, Evan, Kharlamova, Nastya, Israelsson, Lena, Holmdahl, Rikard, Nandakumar, Kutty Selva, Engström, Marianne, Harre, Ulrike, Schett, Georg, Catrina, Anca I, Malmström, Vivianne, Sommarin, Yngve, Klareskog, Lars, Jakobsson, Per-Johan, Lundberg, Karin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448322/
https://www.ncbi.nlm.nih.gov/pubmed/25112157
http://dx.doi.org/10.1186/ar4683