Cargando…

Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint

INTRODUCTION: A major subset of patients with rheumatoid arthritis (RA) is characterized by the presence of circulating autoantibodies directed to citrullinated proteins/peptides (ACPAs). These autoantibodies, which are commonly detected by using an enzyme-linked immunosorbent assay (ELISA) based on...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ossipova, Elena, Cerqueira, Cátia Fernandes, Reed, Evan, Kharlamova, Nastya, Israelsson, Lena, Holmdahl, Rikard, Nandakumar, Kutty Selva, Engström, Marianne, Harre, Ulrike, Schett, Georg, Catrina, Anca I, Malmström, Vivianne, Sommarin, Yngve, Klareskog, Lars, Jakobsson, Per-Johan, Lundberg, Karin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448322/ https://www.ncbi.nlm.nih.gov/pubmed/25112157 http://dx.doi.org/10.1186/ar4683

Ejemplares similares

Targeting of anti-citrullinated protein/peptide antibodies in rheumatoid arthritis using peptides mimicking endogenously citrullinated fibrinogen antigens
por: Fernandes-Cerqueira, Cátia, et al.
Publicado: (2015)

Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism
por: Wigerblad, Gustaf, et al.
Publicado: (2016)

Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides
por: Hansson, Monika, et al.
Publicado: (2012)

IgG Antibodies to Cyclic Citrullinated Peptides Exhibit Profiles Specific in Terms of IgG Subclasses, Fc-Glycans and a Fab-Peptide Sequence
por: Lundström, Susanna L., et al.
Publicado: (2014)

Antibodies to carbamylated α-enolase epitopes in rheumatoid arthritis also bind citrullinated epitopes and are largely indistinct from anti-citrullinated protein antibodies
por: Reed, Evan, et al.
Publicado: (2016)

Antibodies to a Citrullinated Porphyromonas gingivalis Epitope Are Increased in Early Rheumatoid Arthritis, and Can Be Produced by Gingival Tissue B Cells: Implications for a Bacterial Origin in RA Etiology
por: Sherina, Natalia, et al.
Publicado: (2022)

Antibody-induced arthritis: disease mechanisms and genes involved at the effector phase of arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2006)

Platelets derived citrullinated proteins and microparticles are potential autoantibodies ACPA targets in RA patients
por: Xu, Minjie, et al.
Publicado: (2023)

Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition
por: Amara, Khaled, et al.
Publicado: (2013)

Structure and pathogenicity of antibodies specific for citrullinated collagen type II in experimental arthritis
por: Uysal, Hüseyin, et al.
Publicado: (2009)

Type IX collagen deficiency enhances the binding of cartilage-specific antibodies and arthritis severity
por: Carlsen, Stefan, et al.
Publicado: (2006)

Retraction: Monoclonal IgG antibodies generated from joint-derived B cells of RA patients have a strong bias toward citrullinated autoantigen recognition
por: Amara, Khaled, et al.
Publicado: (2019)

Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice
por: Lindh, Ingrid, et al.
Publicado: (2014)

Chronic development of collagen-induced arthritis is associated with arthritogenic antibodies against specific epitopes on type II collagen
por: Bajtner, Estelle, et al.
Publicado: (2005)

Collagen type II (CII)-specific antibodies induce arthritis in the absence of T or B cells but the arthritis progression is enhanced by CII-reactive T cells
por: Nandakumar, Kutty Selva, et al.
Publicado: (2004)

Human NCF1(90H) Variant Promotes IL-23/IL-17—Dependent Mannan-Induced Psoriasis and Psoriatic Arthritis
por: Li, Yanpeng, et al.
Publicado: (2023)

Antibody responses to de novo identified citrullinated fibrinogen peptides in rheumatoid arthritis and visualization of the corresponding B cells
por: Joshua, Vijay, et al.
Publicado: (2016)

Salivary citrullinated proteins in rheumatoid arthritis and associated periodontal disease
por: Tar, Ildikó, et al.
Publicado: (2021)

Cartilage oligomeric matrix protein specific antibodies are pathogenic
por: Geng, Hui, et al.
Publicado: (2012)

Genetic dissection of a major haplotype associated with arthritis reveal FcγR2b and FcγR3 to act additively
por: Vaartjes, Daniëlle, et al.
Publicado: (2020)

Cystatin C influences the autoimmune but not inflammatory response to cartilage type II collagen leading to chronic arthritis development
por: Bäcklund, Alexandra, et al.
Publicado: (2011)

A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2010)

Differences in the Spectrum of Anti–Citrullinated Protein Antibody Fine Specificities Between Malaysian and Swedish Patients With Rheumatoid Arthritis: Implications for Disease Pathogenesis
por: Too, Chun Lai, et al.
Publicado: (2016)

Increased citrullination and expression of peptidylarginine deiminases independently of P. gingivalis and A. actinomycetemcomitans in gingival tissue of patients with periodontitis
por: Engström, Marianne, et al.
Publicado: (2018)

Cartilage oligomeric matrix protein deficiency promotes early onset and the chronic development of collagen-induced arthritis
por: Geng, Hui, et al.
Publicado: (2008)

Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis
por: Snir, Omri, et al.
Publicado: (2014)

Circulating secretory IgA antibodies against cyclic citrullinated peptides in early rheumatoid arthritis associate with inflammatory activity and smoking
por: Roos, Karin, et al.
Publicado: (2016)

Biased TCR gene usage in citrullinated Tenascin C specific T-cells in rheumatoid arthritis
por: Sharma, Ravi K., et al.
Publicado: (2021)

Characterization of chronic relapsing antibody mediated arthritis in mice with a mutation in Ncf1 causing reduced oxidative burst
por: Liang, Peibin, et al.
Publicado: (2022)

Anticitrullinated protein antibodies facilitate migration of synovial tissue-derived fibroblasts
por: Sun, Meng, et al.
Publicado: (2019)

T cells that are naturally tolerant to cartilage-derived type II collagen are involved in the development of collagen-induced arthritis
por: Malmström, Vivianne, et al.
Publicado: (2000)

Associations of antibodies against citrullinated peptides with human leukocyte antigen-shared epitope and smoking prior to the development of rheumatoid arthritis
por: Kokkonen, Heidi, et al.
Publicado: (2015)

Cartilage-binding antibodies initiate joint inflammation and promote chronic erosive arthritis
por: Li, Yanpeng, et al.
Publicado: (2020)

Combination of Two Monoclonal Anti–Citrullinated Protein Antibodies Induced Tenosynovitis, Pain, and Bone Loss in Mice in a Peptidyl Arginine Deiminase‐4–Dependent Manner
por: Krishnamurthy, Akilan, et al.
Publicado: (2022)

Anti-Citrullinated Protein Antibody Reactivity towards Neutrophil-Derived Antigens: Clonal Diversity and Inter-Individual Variation
por: Cîrciumaru, Alexandra, et al.
Publicado: (2023)

Correction: A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis
por: Nandakumar, Kutty Selva, et al.
Publicado: (2011)

Rheumatoid factor isotypes in relation to antibodies against citrullinated peptides and carbamylated proteins before the onset of rheumatoid arthritis
por: Brink, Mikael, et al.
Publicado: (2016)

First exposure to rituximab is associated to high rate of anti-drug antibodies in systemic lupus erythematosus but not in ANCA-associated vasculitis
por: Faustini, Francesca, et al.
Publicado: (2021)

Citrullinated proteins in arthritis: presence in joints and effects on immunogenicity
por: Lundberg, K, et al.
Publicado: (2004)

Serum RANKL levels associate with anti- citrullinated protein antibodies in early untreated rheumatoid arthritis and are modulated following methotrexate
por: Hensvold, Aase Haj, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_1a6ud492nk237og5ek11m6b0ba