Cargando…

Inhibition of lung adenocarcinoma cells by insulin-like growth factor-I receptor and Kirsten rat sarcoma mutations: A mutation analysis with antisense oligodeoxynucleotide

BACKGROUND: Kirsten rat sarcoma (KRAS) mutations are widespread in lung adenocarcinoma patients. The combined utilization of KRAS antisense oligodeoxynucleotide (ASODN) and insulin-like growth factor-I receptor (IGF-IR) may inhibit the proliferation of A549 cell lines of lung adenocarcinoma. METHODS...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Shaoming, Zhao, Lei, Zhang, Jiahui, Zou, Zhiqiang, Du, Peng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448390/ https://www.ncbi.nlm.nih.gov/pubmed/26273371 http://dx.doi.org/10.1111/1759-7714.12176

Ejemplares similares

The Nanotechnology-Based Approaches against Kirsten Rat Sarcoma-Mutated Cancers
por: Andrade, Fernanda, et al.
Publicado: (2023)

Solitary acrometastasis of the phalanx as initial presentation of an oligometastatic Kirsten rat sarcoma viral oncogene homolog-mutated lung adenocarcinoma: a case report
por: Pușcașu, Alexandra-Ioana, et al.
Publicado: (2023)

Kirsten rat sarcoma virus protein overexpression in adenocarcinoma lung: Association with clinicopathological and histomorphological features
por: Pandey, Rahul Kumar, et al.
Publicado: (2020)

Dual-energy spectral CT characteristics in surgically resected lung adenocarcinoma: comparison between Kirsten rat sarcoma viral oncogene mutations and epidermal growth factor receptor mutations
por: Li, Meng, et al.
Publicado: (2019)

MEK inhibitor can reverse the resistance to bevacizumab in A549 cells harboring Kirsten rat sarcoma oncogene homolog mutation
por: Wang, Yuan, et al.
Publicado: (2015)

Not All Kirsten Rat Sarcoma Viral Oncogene Homolog Mutations Predict Poor Survival in Patients With Unresectable Colorectal Liver Metastasis
por: Lin, Zhizun, et al.
Publicado: (2021)

Predicting Kirsten Rat Sarcoma Virus Gene Mutation Status in Patients With Colorectal Cancer by Radiomics Models Based on Multiphasic CT
por: Hu, Jianfeng, et al.
Publicado: (2022)

Kirsten ras mutations in patients with colorectal cancer: the ‘RASCAL II’ study
por: Andreyev, H J N, et al.
Publicado: (2001)

Effect of pseudotype on Abelson virus and Kirsten sarcoma virus-induced leukemia
Publicado: (1978)

The use of synthetic polymers for delivery of therapeutic antisense oligodeoxynucleotides
por: Chirila, Traian V, et al.
Publicado: (2002)

Discovering and Targeting Dynamic Drugging Pockets of Oncogenic Proteins: The Role of Magnesium in Conformational Changes of the G12D Mutated Kirsten Rat Sarcoma-Guanosine Diphosphate Complex
por: Hu, Zheyao, et al.
Publicado: (2022)

Effect of Antisense TGF-β1 Oligodeoxynucleotides in Streptozotocin-Induced Diabetic Rat Kidney
por: Jeong, Hyo Soon, et al.
Publicado: (2004)

Complete response to nivolumab in Kirsten rat sarcoma virus oncogene KRAS-G12C mutant metastatic lung adenocarcinoma: a case report
por: Boby, Jeffrey Mathew, et al.
Publicado: (2022)

Photomodulating RNA cleavage using photolabile circular antisense oligodeoxynucleotides
por: Tang, XinJing, et al.
Publicado: (2010)

Fundamental differences in the equilibrium considerations for siRNA and antisense oligodeoxynucleotide design
por: Lu, Zhi John, et al.
Publicado: (2008)

Computational Screening and Analysis of Lung Cancer Related Non-Synonymous Single Nucleotide Polymorphisms on the Human Kirsten Rat Sarcoma Gene
por: Wang, Qiankun, et al.
Publicado: (2019)

Growth factor-dependent inhibition of normal hematopoiesis by N-ras antisense oligodeoxynucleotides
Publicado: (1992)

Effect of Antisense Oligodeoxynucleotides Glucose Transporter-1 on Enhancement of Radiosensitivity of Laryngeal Carcinoma
por: Yan, Sen-Xiang, et al.
Publicado: (2013)

Antisense oligodeoxynucleotides targeting ATM strengthen apoptosis of laryngeal squamous cell carcinoma grown in nude mice
por: Feng, Jun, et al.
Publicado: (2011)

Clinical outcome of epidermal growth factor receptor‐tyrosine kinase inhibitors therapy for patients with overlapping kirsten rat sarcoma 2 viral oncogene homolog and epidermal growth factor receptor gene mutations
por: Zhang, Hong, et al.
Publicado: (2015)

Integration of signaling pathway and bromodomain and extra-terminal domain inhibition for the treatment of mutant Kirsten rat sarcoma viral oncogene homolog cancer
por: Hamilton, Gerhard, et al.
Publicado: (2023)

Relationship Between (18)F-Fluorodeoxyglucose Uptake and V-Ki-Ras2 Kirsten Rat Sarcoma Viral Oncogene Homolog Mutation in Colorectal Cancer Patients: Variability Depending on C-Reactive Protein Level
por: Lee, Jae-Hoon, et al.
Publicado: (2016)

Phase 1B Study of Momelotinib Combined With Trametinib in Metastatic, Kirsten Rat Sarcoma Viral Oncogene Homolog-Mutated None—Small-Cell Lung Cancer After Platinum-Based Chemotherapy Treatment Failure
por: Barbie, David A., et al.
Publicado: (2018)

Leukemia treatment in severe combined immunodeficiency mice by antisense oligodeoxynucleotides targeting cooperating oncogenes
Publicado: (1995)

Antisense Oligodeoxynucleotide Inhibition as an Alternative and Convenient Method for Gene Function Analysis in Pollen Tubes
por: Liao, Fanglei, et al.
Publicado: (2013)

Effective management of advanced colon cancer genotyping microsatellite stable/microsatellite instable-low with Kirsten rat sarcoma viral oncogene mutation using nivolumab plus ipilimumab combined with regorafenib and irinotecan: A case report
por: Cui, Yingqiang, et al.
Publicado: (2021)

Concomitant occurrence of EGFR (epidermal growth factor receptor) and KRAS (V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog) mutations in an ALK (anaplastic lymphoma kinase)-positive lung adenocarcinoma patient with acquired resistance to crizotinib: a case report
por: Rossing, Henrik H, et al.
Publicado: (2013)

Targeting Mutant Kirsten Rat Sarcoma Viral Oncogene Homolog in Non-Small Cell Lung Cancer: Current Difficulties, Integrative Treatments and Future Perspectives
por: Li, Jia-Xin, et al.
Publicado: (2022)

Kirsten murine sarcoma virus abolishes interferon gamma-induced class II but not class I major histocompatibility antigen expression in a murine fibroblast line
Publicado: (1988)

T315I-mutated myeloid sarcoma
por: Zhang, Yumeng, et al.
Publicado: (2019)

Translation of stable hepadnaviral mRNA cleavage fragments induced by the action of phosphorothioate-modified antisense oligodeoxynucleotides
por: Hasselblatt, Peter, et al.
Publicado: (2005)

Bioinformatics Data Mining Repurposes the JAK2 (Janus Kinase 2) Inhibitor Fedratinib for Treating Pancreatic Ductal Adenocarcinoma by Reversing the KRAS (Kirsten Rat Sarcoma 2 Viral Oncogene Homolog)-Driven Gene Signature
por: Liu, Li-Wei, et al.
Publicado: (2020)

Kirsten Ras* oncogene: Significance of its discovery in human cancer research
por: Tsuchida, Nobuo, et al.
Publicado: (2016)

Class II histocompatibility antigen expression in human melanocytes transformed by Harvey murine sarcoma virus (Ha-MSV) and Kirsten MSV retroviruses
Publicado: (1986)

Expression of NR1 subunit of NMDA receptor and PSD-93/95 in rat hippocampus affected by NR1/NR2 antisense oligodeoxynucleotide
por: Vrajová, Monika, et al.
Publicado: (2010)

Knockdown of Inhibitory Guanine Nucleotide Binding Protein Giα‐2 by Antisense Oligodeoxynucleotides Attenuates the Development of Hypertension and Tachycardia in Spontaneously Hypertensive Rats
por: Ali El‐Basyuni, Yousra, et al.
Publicado: (2016)

Antisense oligodeoxynucleotide against human telomerase reverse transcriptase inhibits the proliferation of Eca-109 esophageal carcinoma cells
por: FAN, XIANG-KUI, et al.
Publicado: (2014)

Synergistic cytotoxicity of bcl-2 antisense oligodeoxynucleotides and etoposide, doxorubicin and cisplatin on small-cell lung cancer cell lines.
por: Zangemeister-Wittke, U., et al.
Publicado: (1998)

Therapeutic efficacy of liposomal Grb2 antisense oligodeoxynucleotide (L-Grb2) in preclinical models of ovarian and uterine cancer
por: Lara, Olivia D., et al.
Publicado: (2020)

Antisense oligodeoxynucleotides against dynamin-related protein 1 reduce remifentanil-induced hyperalgesia by modulating spinal N-methyl-D-aspartate receptor expression in rats
por: Zhou, Songyi, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_ggadgf0oldqvikamgu62ebv52u