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Effects of histone deacetylase inhibitor trichostatin A combined with cisplatin on apoptosis of A549 cell line

BACKGROUND: Histone deacetylase (HDAC) inhibitors combined with other drugs for the treatment of malignant tumors are used more and more widely. In this study, we investigated the effect of trichostatin A (TSA), a HDAC inhibitor, in combination with cisplatin, a cytotoxic chemotherapy agent, on the...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, Jiang, Shu-Juan, Shang, Bin, Jiang, Hong-Juan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448485/
https://www.ncbi.nlm.nih.gov/pubmed/26273359
http://dx.doi.org/10.1111/1759-7714.12167