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A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient

BACKGROUND: The elderly represent a unique challenge for the effects of regional anesthesia, and very few cases of block onset delay have been described. Their delayed response is attributed to a number of factors that include: Physiologic deterioration, musculoskeletal contractures, degenerative jo...

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Autores principales: Ghaly, Ramsis F., Anantamongkol, Utchariya, Candido, Kenneth D., Knezevic, Nebojsa Nick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448518/
https://www.ncbi.nlm.nih.gov/pubmed/26060597
http://dx.doi.org/10.4103/2152-7806.157658
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author Ghaly, Ramsis F.
Anantamongkol, Utchariya
Candido, Kenneth D.
Knezevic, Nebojsa Nick
author_facet Ghaly, Ramsis F.
Anantamongkol, Utchariya
Candido, Kenneth D.
Knezevic, Nebojsa Nick
author_sort Ghaly, Ramsis F.
collection PubMed
description BACKGROUND: The elderly represent a unique challenge for the effects of regional anesthesia, and very few cases of block onset delay have been described. Their delayed response is attributed to a number of factors that include: Physiologic deterioration, musculoskeletal contractures, degenerative joint disease, autonomic regulatory dysfunction, cognitive dysfunction, altered pharmacokinetics, and pharmacodynamics of local anesthetics and adjuvants. CASE DESCRIPTION: In this report we present the rare case of 45-min delay between the administration and onset of action of a subarachnoid blockade in a 103-year-old female, who was scheduled for left hip pinning, for repair of a femoral neck fracture. Patient received an injection of hyperbaric bupivacaine, 1.5 ml of 0.75% (11.25 mg), with 15 mcg of fentanyl into the subarachnoidal space and underwent the surgical procedure without complications. CONCLUSIONS: Delayed responses to subarachnoid anesthesia can be expected in extremely elderly patients. Anesthetic procedures should be monitored and managed on a case-by-case basis.
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spelling pubmed-44485182015-06-09 A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient Ghaly, Ramsis F. Anantamongkol, Utchariya Candido, Kenneth D. Knezevic, Nebojsa Nick Surg Neurol Int Case Report BACKGROUND: The elderly represent a unique challenge for the effects of regional anesthesia, and very few cases of block onset delay have been described. Their delayed response is attributed to a number of factors that include: Physiologic deterioration, musculoskeletal contractures, degenerative joint disease, autonomic regulatory dysfunction, cognitive dysfunction, altered pharmacokinetics, and pharmacodynamics of local anesthetics and adjuvants. CASE DESCRIPTION: In this report we present the rare case of 45-min delay between the administration and onset of action of a subarachnoid blockade in a 103-year-old female, who was scheduled for left hip pinning, for repair of a femoral neck fracture. Patient received an injection of hyperbaric bupivacaine, 1.5 ml of 0.75% (11.25 mg), with 15 mcg of fentanyl into the subarachnoidal space and underwent the surgical procedure without complications. CONCLUSIONS: Delayed responses to subarachnoid anesthesia can be expected in extremely elderly patients. Anesthetic procedures should be monitored and managed on a case-by-case basis. Medknow Publications & Media Pvt Ltd 2015-05-26 /pmc/articles/PMC4448518/ /pubmed/26060597 http://dx.doi.org/10.4103/2152-7806.157658 Text en Copyright: © 2015 Ghaly RF. http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Ghaly, Ramsis F.
Anantamongkol, Utchariya
Candido, Kenneth D.
Knezevic, Nebojsa Nick
A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
title A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
title_full A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
title_fullStr A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
title_full_unstemmed A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
title_short A rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
title_sort rare case of delayed subarachnoid anesthetic blockade effects in a 103-year-old female patient
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448518/
https://www.ncbi.nlm.nih.gov/pubmed/26060597
http://dx.doi.org/10.4103/2152-7806.157658
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