A novel inhibitory mechanism of MRTF-A/B on the ICAM-1 gene expression in vascular endothelial cells

The roles of myocardin-related transcription factor A (MRTF-A) and MRTF-B in vascular endothelial cells are not completely understood. Here, we found a novel regulatory mechanism for MRTF-A/B function. MRTF-A/B tend to accumulate in the nucleus in arterial endothelial cells in vivo and human aortic...

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Detalles Bibliográficos
Autores principales: Hayashi, Ken’ichiro, Murai, Toshiyuki, Oikawa, Hiroki, Masuda, Tomoyuki, Kimura, Kazuhiro, Muehlich, Susanne, Prywes, Ron, Morita, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4448521/
https://www.ncbi.nlm.nih.gov/pubmed/26024305
http://dx.doi.org/10.1038/srep10627

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